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加拿大临床生物化学学会目前推荐的实验室危急值资料 

Laboratory Practice Guidelines of the Ontario Society of Clinical Chemists
May, 1999
Number 2

Reporting Critical Values

Most laboratories have a list of tests with critical reporting values. When a laboratory test yields a result that exceeds the critical value, the laboratory must immediately verify its accuracy and inform the appropropriate medical staff of the result. There are differences of opinion as to what constitutes a critical (life threatening) value. Drugs are often added to such critical lists. Critical drug levels usually merit keen attention and immediate action but they may not be strictly life threatening. Each laboratory should prepare, in cooperation with its medical staff, a list of critical values and a process to follow in reporting these values.


Recommended Critical Values (Tests)

Test  

Lower Limit

Upper Limit

Units

Blood Gases
pH 7.20 7.50
pCO2 20 60 mm Hg
pO2 40 -- mm Hg
Electrolytes
Na+ 120 160 mmol/L
K+ 3.0 6.0 mmol/L
Cl 80 125 mmol/L
HCO3-   15 35 mmol/L
Glucose 2.5 25 mmol/L
Creatinine -- 1500* umol/L
Osmolality 250 330 mosmol/Kg
Calcium 1.5 3.0 mmol/L
Magnesium 0.4 3.0 mmol/L
Phosphate 0.4 3.0 mmol/L

Recommended Critical Values (Drugs)

Drug

Upper Limit 

Units

Analgesics    
Salicylates 2.0 mmol/L
Acetaminophen  60** umol/L
     
Anti-Epileptic Drugs    
Carbamazepine  63 umol/L
Phenobarbital  225 umol/L
Phenytoin 120 umol/L
Valproate 1400 umol/L
     
Aminoglycosides    
Amikacin   40 mg/L
Gentimicin 10 mg/L
Tobramycin 10 mg/L
Vancomycin 470 mg/L
     
Others    
 Digoxin 3.8 nmol/L
Lithium 1.5 mmol/L
Theophylline 110 umol/L
     
     
     

   Tests that are printed in bold must be included in any list of critical reporting values.
   * First time Creatinine:  200 umol/L.
   ** Four hours post-ingestion.

  Recommendations:

  1. Develop a list of critical test results and reporting procedures in consultation with your medical staff.
  2. Train your staff in appropriate verification and reporting procedures when test results exceed critical values.

____________________

以上为加拿大临床生物化学学会目前推荐资料,供参考。

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